ZetaMet™ (Zeta-BC-003) is a synthetic, small-molecule, developed via a proprietary control release carrier developed to resolve bone lesions, inhibiting pain while regenerating bone, with the potential to increase survival rates. The U.S. Food and Drug Administration recently awarded ZetaMet™ (Zeta-BC-003) Breakthrough Designation for the treatment of metastatic bone cancer. Currently, ZetaMet™ (Zeta-BC-003) has been approved by Health Canada for a clinical trial which is currently enrolling for the treatment of metastatic breast cancer lesions to the spine. Zetagen scientists have discovered an entirely new pathway for this established molecule which, if proven successful in human clinical trials, could create a new treatment paradigm for patients living with metastatic bone lesions. Enrollment for this study is scheduled for Q1-2024.
ZetaMAST™ (Zeta-MBC-005)
ZetaMAST™ (Zeta-MBC-005) is a proprietary novel drug being designed for patients with unresectable, multifocal breast cancer metastases to the liver. ZetaMAST™ (Zeta-MBC-005) can be administered as a percutaneous injection utilizing a proprietary hydrogel carrier containing a precise, tailored concentration of our small molecule. Preclinical studies have demonstrated ZetaMAST™ (Zeta-MBC-005) may cease lesion growth, with the goal of enabling improved quality of life as part of a cancer treatment program, including longevity.
Musculoskeletal
ZetaFuse™
ZetaFuse™ is the first synthetic, small molecule, osteo-inductive biologic, to safely aid bone healing of spinal fusions. The FDA has awarded ZetaFuse™ Breakthrough Device Designation[1] for the complete spinal column.
ZetaSet™
ZetaSet™ is the first synthetic, osteo-inductive, biologic designed specifically for the treatment of osteoporotic fractures, high energy injuries with bone defects, and for patients with fractures of the tibial plateau (knee) and plafond (ankle).
ZetaBase®
ZetaBase® is an osteo-conductive and osteo-promotive therapy, intended for the use as a bone void filler for bony voids or gaps that are not intrinsic to the stability of the bony structure. Pending 510K approval 2H-2022.
Craniomaxillofacial
ZetaDent™
ZetaDent™ is an osteo-inductive biologic intended to promote bone formation as a part of localized ridge augmentation procedures prior to dental implant placement, alveolar ridge reconstruction procedures for prosthetic treatment, and for filling of bone defects in the oral cavity.
ZetaSet™
ZetaSet™ is the first synthetic, osteo-inductive, biologic designed specifically for the treatment of osteoporotic fractures, high energy injuries with bone defects, and for patients with fractures of the tibial plateau (knee) and plafond (ankle).
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