ZetaMet Settable™ is being designed for the treatment of patients with metastatic lesions that have or will result in a Skeletal-Related Event, (SRE) including fractures and spinal cord compression.
A vertebroplasty procedure is a way to treat vertebral body compression fractures, which are small breaks in the thick mass of bone that make up the front part of the spinal column “the vertebral body”. Vertebral body fractures lead to the collapse or compression of a vertebrae, causing the spine to shorten and curve forward, and result in pain and kyphosis (hunched over deformity). Thinning of bone, or osteoporosis is the main cause of vertebral compression fractures. Pathologic fractures relating to spinal tumors may also be a cause.
ZetaMet Settable™ will be administered via a minimally invasive percutaneous vertebroplasty outpatient procedure.