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Zetagen Therapeutics, Inc. Awarded $300,000 USD Grant from the National Cancer Institute (NCI) for Phase I Study of Novel, Adjuvant Implant for Post-Metastatic Skeletal Lesions

5 September 2018
  • U.S.-based biopharmaceutical company has discovered and patented a novel molecular pathway intended to treat metastatic bone lesions
  • Grant will allow for Phase I validation study of ZetaMet™ via a proprietary, drug eluting implant
  • Company’s intellectual property pipeline targets other oncologic treatments for Skeletal-Related Events (SRE’s) and osteologic interventions

September 5, 2018– (Syracuse, New York) - Zetagen Therapeutics, Inc., a private, US-based biopharmaceutical company dedicated to driving breakthrough innovation in the treatment of metastatic bone cancers and osteologic interventions, announced today its award of a $300,000 (USD) grant from the National Cancer Institute of the National Institutes of Health (NIH). The grant will be used for a Phase I validation study of the Company’s proprietary, drug-eluding implant called ZetaMet™. ZetaMet™ is a synthetic, small-molecule, inductive biologic being developed to suspend tumor growth and regrow bone.

“We are pleased that the National Cancer Institute, through this award, has recognized the potential ZetaMet™ may hold for treating metastatic bone lesions,” said Nikhil Thakur, MD, CMO of Zetagen Therapeutics, Inc. “Osteolytic metastases are among the most challenging of cancers to treat as they both destroy bone and cause debilitating pain in patients.”

The grant is part of the Small Business Innovation Research Program (SBIR), a three-phase award system created by the Federal Government for small businesses to engage in research and development that has the potential for commercialization and public benefit. Zetagen exclusively licensed its platform technology from the State University of New York in 2016. The Company’s Phase I validation study will begin in Q4 2018.

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About zetagen Therapeutics

Founded in 2015, Zetagen is a private, clinical-stage, biopharmaceutical company dedicated to driving breakthrough innovation in the treatment of metastatic bone cancers and osteologic interventions. Our multi-patented, ZetaMet™ technology is a first-of-its kind molecular pathway designed to suspend cancer, inhibit pain, and regenerate bone. Zetagen exclusively-licensed the platform technology from the State University of New York in 2016. This novel therapy, a drug-eluting implant technology, has successfully passed its preclinical trials and is being prepared for its first human clinical trial in early 2022. In addition to ZetaMet™, the Company’s pipeline includes other oncologic treatments for Skeletal Related Events (SREs), i.e., ZetaMet™ Flowable™ and ancillary osteologic treatments including, ZetaFuse™, ZetaSet™, ZetaDent™ and ZetaBase™. To learn more, visit www.zetagen.com  

Forward-Looking Statements

This press release contains certain forward-looking statements with the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company’s product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature.  These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management’s current beliefs and assumptions. 
Source: Zetagen Therapeutics, Inc.
SUNY Biotech Accelerator
841 E Fayette Street, Suite 1100
Syracuse, NY 1321
Investor Inquiries:
Zetagen Therapeutics, Inc.
Media Inquiries:
McDougall Communications on Behalf of Zetagen Therapeutics, Inc.
Elizabeth Harness, Senior Consultant, elizabeth@mcdougallpr.com Phone: +1-585-435-7379
Dan Smith, Senior Counselor, dan@mcdougallpr.com Phone: +1-585-967-2111