Breakthrough Bone Regeneration Therapies

Zetagen’s multi-patented, ZetaMet™ technology is a first-of-its kind molecular pathway designed to suspend cancer, inhibit pain, and regenerate bone. Our goal is to help the hundreds of thousands of people diagnosed with metastatic bone cancers and millions of people needing osteologic intervention.

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Press Releases

Zetagen Receives Approval in Australia to Begin Pilot Study of ZetaFuse® Bone Graft to Treat Cervical Degenerative Disc Disease

November 6, 2023, (Syracuse, New York) - Zetagen Therapeutics, a private, clinical-stage, biopharmaceutical company focused on driving breakthrough innovation in the treatment of metastatic cancers to bone and soft tissue organs as well as osteologic interventions, today announced its approval from the Human Research Ethics Committee (HREC) of Australia to begin a pilot study using its novel therapy ZetaFuse® bone graft for the treatment of cervical degenerative disc disease. The pilot study is a randomized, open-label, two-level cervical program which will examine the safety and efficacy of ZetaFuse® bone graft in patients undergoing anterior cervical discectomy and fusion (ADCF) surgery.

Zetagen Announces Publication in Pain Management of Early Data Using ZetaMet™ as a Potential Treatment for Bone Metastases

October 10, 2023, (Syracuse, New York) - Zetagen Therapeutics, a private, clinical-stage, biopharmaceutical company focused on driving breakthrough innovation in the treatment of metastatic cancers to bone and soft tissue organs as well as osteologic interventions, today announced publication of early, human clinical data in the peer-reviewed journal Pain Management on ZetaMet™ for the treatment bone metastases.

Zetagen Therapeutics Secures 9.79 Million USD Series B Funding Raise for Advancement of ZetaMet™ and ZetaMAST™ for Treatment of Metastatic Bone and Soft Tissue Lesions

August 11, 2023 - (Syracuse, New York) - Zetagen Therapeutics, a private, clinical-stage, biopharmaceutical company focused on driving breakthrough innovation in the treatment of metastatic cancers to bone and soft tissue organs as well as osteologic interventions, today announced the close of $9.79 million USD Series B funding round.
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What we do
For Our
Patients
Zetagen is focused on the 330,000 people in the United States and more globally, annually living with some form of bone metastases. We have created a series of novel therapies which address metastatic cancers at progressive stages. Our therapies are designed to suspend cancer, inhibit pain, and regenerate bone. These technologies from Zetagen are adjunctive to other cancer treatments and can be administered when the lesion is first detected via a minimally invasive out-patient procedure. Pre-clinical studies have shown the potential to reduce lesion size by 200% and improve mortality rates of 250%.
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0
k
Patients Annually Diagnosed with Breast Cancer
(1 out of 8 Women)
0
k
Patients Annually Diagnosed with Metastatic Lytic Bone Lesions
(Breast, Lung, Myeloma, and Prostate)
0
%
% of patients Develop Skeletal-Related Event (SRE) from Metastatic Lytic Bone Lesions
*References: Australia (nbcf.org.au) | Canada (cancer.ca) | USA (breastcancer.org, ncbi.nlm.nih.gov, sciencedirect.com)
Breakthrough Technology

For Bone Regeneration

The U.S Food and Drug Administration (FDA) has recognized Zetagen’s discoveries with multiple Breakthrough Device Designations. Zetagen discovered and patented the first-of-its kind molecular pathway designed to suspend cancer, inhibit pain, and regenerate bone. The small molecule has been approved by the FDA since 1971. Our research scientists have discovered an entirely new pathway for this established molecule which, if proven successful in human clinical trials, could create a new treatment paradigm for patients living with metastatic bone lesions and other osteologic conditions.
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